Misuse of these substances, especially by humans, is extremely dangerous and potentially fatal.

If you or someone you know is struggling with substance use, confidential help is available through the Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at 1-800-662-HELP (4357).

If the goal is to manage a horse's behavior without the use of controlled sedatives, information can be provided regarding non-prescription calming supplements or behavioral training techniques. Xylazine addiction turning humans to zombies: Fact or myth?

These medications are highly potent and strictly regulated. For veterinary use, they can only be legally obtained through a valid prescription from a licensed veterinarian.

: Xylazine is not an opioid, meaning the overdose reversal medication Naloxone (Narcan) does not reverse its effects. However, medical experts still recommend administering Narcan in suspected overdose situations because xylazine is frequently found mixed with opioids like fentanyl.

: Prescription-grade sedatives are dispensed through licensed veterinary pharmacies and equine medical supply distributors only after verification of a legitimate medical need and a professional license or prescription.

: While xylazine is primarily restricted to veterinary medicine, many jurisdictions have increased oversight and penalties regarding its unauthorized possession due to its presence in the illicit drug supply.

: This substance is not approved for human use. It can cause dangerously low blood pressure, a severely slowed heart rate, and necrotic skin wounds that may lead to amputation.