If you are experiencing stability issues with newer hardware, check the BIOS & Firmware section on the ASUS site.
Most P5QL boards (PRO, SE, E, EM, EPU) use a similar set of core drivers: p5ql drajver
Most components (LAN, Audio) may be automatically recognized by modern Windows versions, but you might need the ATK0110 driver installed in "Compatibility Mode". If you are experiencing stability issues with newer