Once Wine is installed, you don't "open" Wine; you use it to open your Windows file.
Most modern Linux distributions include 64-bit support by default, but you should ensure both architectures are available for maximum compatibility. Download WEIN 64bit exe
Look for wine-stable or wine-devel 64-bit packages. Once Wine is installed, you don't "open" Wine;
Type wine64 --version to confirm it is installed correctly. For macOS (Catalina 10.15 and newer) Once Wine is installed