: When thrombolysis is contraindicated or fails, options include catheter-directed thrombectomy or surgical embolectomy. Prognosis and Follow-Up
Patients with a first episode of unprovoked PE usually require anticoagulation for at least 3 to 6 months. Extended therapy may be necessary if persistent risk factors exist. Long-term monitoring is essential to detect rare complications like , which can present as persistent breathlessness months after the initial event.
Acute Pulmonary Embolism (PE) is a critical cardiovascular emergency characterized by the sudden obstruction of a pulmonary artery, typically by a blood clot originating from deep vein thrombosis (DVT) in the lower limbs. As a leading cause of in-hospital mortality, its management requires rapid risk stratification and adherence to standardized clinical guidelines. Pathophysiology and Etiology Download Embolie pulmonaire aiguГ« pdf
: For high-risk (hemodynamically unstable) patients, systemic thrombolysis (e.g., Alteplase) is recommended to rapidly dissolve the clot.
Treatment strategies are dictated by the patient's hemodynamic stability and risk category. : When thrombolysis is contraindicated or fails, options
Diagnosis is often challenging because symptoms like dyspnea and chest pain are non-specific.
: Obstruction causes a ventilation-to-perfusion ( ) mismatch, leading to hypoxemia and respiratory distress. Diagnostic Framework systemic thrombolysis (e.g.
) scans are alternatives for patients with renal issues or contrast allergies. Management and Treatment
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