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While highly effective, prednisolone is not without risks. Long-term use or high administration levels can lead to side effects such as increased thirst, weight gain, and a weakened immune system. It is vital that the medication is never stopped abruptly; instead, a veterinarian will typically manage the reduction of the medication to allow the cat’s adrenal glands to resume natural hormone production.

: Applied to the inner ear for cats that refuse oral medication.

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: Often flavored (e.g., chicken, beef, or marshmallow) to mask the naturally bitter taste of the medication. While highly effective, prednisolone is not without risks

The versatility of prednisolone stems from its ability to mimic natural hormones produced by the adrenal glands, effectively suppressing overactive immune responses and reducing systemic inflammation.

: It is frequently used for feline asthma and inflammatory bowel disease (IBD), where it helps soothe irritated tissues. : Applied to the inner ear for cats

Prednisolone is a prescription-only, controlled corticosteroid for cats, which can be acquired through licensed veterinary pharmacies such as Chewy, 1-800-PetMeds, or Dutch. These retailers require a valid prescription from a veterinarian, often handling the verification process directly with the clinic. The Critical Role of Prednisolone in Feline Medicine